The Lake is an amazing, unique aircraft. There's nothing else in the certified airframe world like it. I've got about 600h on mine, have flown it throughout Canada's North into some spectacular places only accessible by air, have spent many a happy hour with my wife or with my kids at anchor on some northern lakes and rivers fishing to our hearts content, and I've also taken it into the urban jungles of Toronto, Montreal, Boston, Washington DC, etc like it belonged there.
All airplanes are compromises, but the Lake manages to hit a sweet spot for those whose mission profile is getting out of town to a beach or cottage on a lake for a few days, and then back to civilization. Sure, conventional floats are easier to dock than a Buc, but they are kind of ungainly maneuvering on the water under power, especially with a little crosswind. Conventional amphib float-equipped aircraft can land on a strip, but they do it awkwardly and with a significant hit on both payload and performance. In contrast, the Buc lets you operate like a retractable gear aircraft when that's what's required, and like a powerboat when you are on the water.
That said, there's a few oddities about the aircraft. It loads through the split windshield which IMHO is an improvement over a single door Mooney, but it's still not a Cessna in that regard. The seating - close to the floor - will be familiar to a Mooney pilot. The pylon engine, pusher arrangement is brilliant and gets you off the water like a charm, but it does add considerable drag to the airframe once you are in the cruise mode of flight. The IO-360 in a Buc gets you about 100 kta on 10-12 gph....much less than what you get in a Mooney with the same engine. In an emergency engine-out situation, the guide ratio is terrible - look down - that's where you're landing, but the amphib capability means that everything is pretty much a runway in a pinch. Some attention is required on and off "the step" during takeoff and landing to ensure that you don't 'porpoise' off the swells, but handling on the water below flying speeds is brilliant - it seriously drives like a boat.
Maintenance is a bit expensive if you are operating off strip, where some wear and tear is inevitable. Like Mooney, the Lake factory is in mothballs, but parts supplies are very good and there are a network of 'Lake Masters' who provide excellent factory-trained service, and an excellent on-line community of Lake owners who are free with opinions and advice.
Won't ever regret jumpin' in a Lake.