What works for us:
G500 TXi, GTN 750, GNS 530 (WAAS), GI 275 Standby, GFC 500 Auto-pilot. And, the IPad. (Don’t forget the USB ports!)
Starting at 7500’ in cruise yesterday, we were able to GPS navigate to the IAF for the RNAV GPS approach, descend from cruise in VNAV to the IAF and also the subsequent published step downs, follow the approach course to intercept the GP (glide path) and then descend to minimums while working only the throttle, the gear and the flaps. Occasionally the speedbrakes. This is a complete game changer for GA. The FMA’s (scoreboard) provide complete confidence in the workings of the AP by telling you at all times what pitch and roll and altitude modes are currently activated, and which ones are armed.
The missed approach was accomplished solely with the G/A button, the throttle, the gear and flap switches with the AP remaining engaged the entire time. The airplane climbed to the missed approach altitude, leveled off, and entered the missed approach hold with no issue.
I recommend changing the default VNAV descent angle in the GTN750 from 3 degrees to 2 degrees or less. Three degrees is too steep for piston airplanes without very low power settings and higher vertical speeds. Two degrees or less results in cruise descent rates from about 400-600 fpm which is nice for passengers and power settings.
Two weeks ago we did the same in snow and ice (to minimums) giving the TKS system a workout. (120 knot minimum when using this system)
This panel has satellite (and ADSB) weather which is nice because of the faster update rates but it’s not a MUST have.
If you are going to fly your airplane in the weather and/ or travel long distances in it. I highly recommend moving your panel to the modern instruments. And, as many others have said, it’s best if you can do it all at once. It’s a functional, situational awareness and safety leap forward.